Protivovirusnoye sredstvo, okazыvayet immunomoduliruyuщyee i protivogrippoznoye deystviye, spetsificheski podavlyayet virusы grippa A i V.

Obladayet interferonindutsiruyuщimi svoystvami, stimuliruyet gumoralnыye i kletochnыye reaktsii immuniteta, fagotsitarnuyu funktsiyu makrofagov, povыshayet ustoychivost organizma k virusnыm infektsiyam. Preduprejdayet razvitiye postgrippoznыx oslojneniy, snijayet chastotu obostreniy xronicheskix zabolevaniy, normalizuyet immunologicheskiye pokazateli. Protivovirusnoye deystviye obuslovleno podavleniyem sliyaniya lipidnoy obolochki virusa s kletochnыmi membranami pri kontakte virusa s kletkoy. Terapevticheskaya effektivnost pri grippe proyavlyayetsya v snijenii intoksikatsii i vыrajennosti kataralnыx yavleniy, ukorochenii periodov lixoradki i obщyey prodoljitelnosti zabolevaniya. Otnositsya k malotoksichnыm lekarstvennыm sredstvam ( LD 50>4 g/kg). Ne okazыvayet kakogo-libo otritsatelnogo vozdeystviya na organizm cheloveka pri peroralnom primenenii v rekomenduyemыx dozax.

Absorbtsiya - bыstraya. Bыstro raspredelyayetsya po organam i tkanyam. TC_max pri priyeme v doze 50 mg - 1.2 ch, 100 mg - 1.5 ch. Metaboliziruyetsya v pecheni. T_1/2 - 17-21 ch. Okolo 40% vыvoditsya v neizmenennom vide, v osnovnom s jelchyu (38.9%) i v neznachitelnom kolichestve pochkami (0.12%). V techeniye pervыx sutok vыvoditsya 90% ot vvedennoy dozы.

Profilaktika i lecheniye u vzroslыx i detey:

• gripp, vыzvannыy virusami A i V;
• ostrыye respiratornыye virusnыye infektsii (ORVI) (v t.ch. oslojnennыye bronxitom, pnevmoniyey);
• vtorichnыye immunodefitsitnыye sostoyaniya.

Kompleksnaya terapiya xronicheskogo bronxita, pnevmoniya i retsidiviruyuщyey gerpeticheskoy infektsii.

Profilaktika posleoperatsionыx infektsionnыx oslojneniy i normalizatsiya immunnogo statusa u vzroslыx.

Vnutr, do priyema piщi. Razovaya doza: detyam ot 3 do 6 let - 50 mg, ot 6 do 12 let - 100 mg, starshe 12 let i vzroslыm - 200 mg (2 tabletki po 100 mg ili 4 tabletki po 50 mg).

Dlya nespetsificheskoy profilaktiki

Pri neposredstvennom kontakte s bolnыmi grippom i drugimi ORVI: detyam ot 3 do 6 let - 50 mg, ot 6 do 12 let - 100 mg, starshe 12 let i vzroslыm - 200 mg 1 raz vden v techeniye 10-14 dney.

V period epidemii grippa i drugix ORVI, dlya preduprejdeniya obostreniy xronicheskogo bronxita, retsidiva gerpeticheskoy infektsii: detyam ot 3 do 6 let - 50 mg, ot 6 do 12 let - 100 mg, starshe 12 let i vzroslыm - 200 mg 2 raza v nedelyu v techeniye 3 nedel.

Profilaktika posleoperatsionnыx oslojneniy: detyam ot 3 do 6 let- 50 mg, ot 6 do 12 let- 100 mg, starshe 12 let i vzroslыm - 200 mg za 2 dni do operatsii, zatem na 2 i 5 den posle operatsii.

Dlya lecheniya

Gripp, drugiye ORVI bez oslojneniy: detyam ot 3 do 6 let - 50 mg, ot 6 do 12 let - 100 mg, starshe 12 let i vzroslыm - 200 mg 4 raza v den (kajdыye 6 chasov) v techeniye 5 dney.

Gripp, drugiye ORVI s razvitiyem oslojneniy (bronxit, pnevmoniya i drugiye): detyam ot 3 do 6 let - 50 mg, ot 6 do 12 let - 100 mg, starshe 12 let i vzroslыm - 200 mg 4 raza v den (kajdыye 6 chasov) v techeniye 5 dney, zatem razovuyu dozu 1 raz v nedelyu v techeniye 4 nedel.

Allergicheskiye reaktsii.

• detskiy vozrast (do 3 let);
• nalichiye takix zabolevaniy, kak neperenosimost galaktozы, defitsit laktazы, glyukozo-galaktoznaya malabsorbtsiya;
• povыshennaya chuvstvitelnost k komponentam preparata.

Pri naznachenii s drugimi lekarstvennыmi sredstvami otritsatelnыx effektov ne bыlo otmecheno.

Ne proyavlyayet tsentralnoy neyrotropnoy aktivnosti i mojet primenyatsya v meditsinskoy praktike v profilakticheskix tselyax u prakticheski zdorovыx lits razlichnыx professiy, v tom chisle trebuyuщix povыshennogo vnimaniya i koordinatsii dvijeniy (voditeli transporta, operatorы i tak daleye).

Spisok B. Pri temperature ne vыshe 25°S. V nedostupnom dlya detey meste.

Ne otmechena.

Bez retsepta.